I Interviewed Dr. Bill Andrews, the Man Trying to Cure Aging

Dr Bill Andrews Interview

Last week I sat down with Dr. Bill Andrews, and I think it might be the most important hour I've recorded since starting this project.

The full video is coming soon. Here's who he is and what we covered, so you know why you should block out the time.

Dr Bill Andrews InterviewWho Is Dr. Bill Andrews?

Bill Andrews has been trying to cure aging since he was ten years old, when his father asked him whether he'd be interested in solving it. He's almost 75 now and still in the lab every day.

He runs Sierra Sciences. He holds more than 50 patents, and he was a key inventor on human growth hormone, tissue plasminogen activator, Betaseron and erythropoietin — drugs that are in hospitals right now. He was National Inventor of the Year for his cancer research. He co-starred in the documentary The Immortalist, which made the Academy's top ten for documentary in 2014.

He also held the world speed record for barefoot water skiing, and the record for the most hundred-mile ultramarathons run in a single year. I'm 71 and I felt lazy sitting across from him.

If you want to understand aging at the mechanical level — not the supplement-influencer level, the actual biology — he is arguably the best explainer alive.

What We Talked About

A preview of what's in the interview:

  • Why telomeres actually shorten — and why the shoelace analogy everybody repeats is wrong. His bricklayer explanation finally made it click for me.
  • The ride ticket math. You get 100 tickets as a single-cell embryo. Bill told me how many you have left by the time you're born, and the number genuinely stopped me cold on camera.
  • The hard ceiling. There's a maximum human lifespan you cannot exceed no matter how perfect your protocol is. He says what it is and why.
  • How to spot a fake telomere product. This is the most useful thing in the whole hour. There's one question you can ask any company selling telomere support — and Bill says if they can't answer it, their product may be accelerating your aging. I'd never have known to ask.
  • Telomerase and cancer. Everybody assumes lengthening telomeres causes cancer. Bill argues the exact opposite, and his reasoning is airtight.
  • What Bill Andrews takes himself — his actual daily stack, including one thing he says most people are wasting their money on.
  • The price tag on curing aging. He named a dollar figure and a timeline. Both are smaller than you'd think.
  • Liz Parrish, gene therapy, and the fight to let dying people try treatments that haven't cleared the FDA.

Why This One Matters to Me

I'm 71. My whole bet is that I can stay sharp and functional long enough to reach the wave — the point where science starts adding years back faster than I lose them. Aubrey de Grey calls it longevity escape velocity. Dr. Terry Grossman puts it better: live long enough to live forever.

Bill Andrews is one of the handful of people on earth actually working on the thing that decides whether that bet pays off. And he gives nearly all of it away for free.

Thanks to Liz Parrish for putting us together. If you haven't watched her episode yet, start here.

The Video Is Coming Soon

Keep an eye out — I'll post the full interview here and on my YouTube channel shortly. Subscribe so you don't miss it.

Everything I track is public and free at GaryLeland.com.

A note from Gary: I'm not a doctor, and I'm definitely not your doctor. Nothing here is medical advice. Check with your doctor before you copy anything I do.

Stay sovereign, stay healthy.

The Hume Scale Says I’m 53. My Blood Says 56. I’m 71.

Hume Scale

I get on a scale once a week. Most people do it to check one number. I do it to check about a dozen.

This is my Hume scale review after using it daily in my 200 Year Life Project. The Hume Body Pod is a smart scale that runs a bioelectrical impedance scan every time I step on it — weight, body fat percentage, lean mass by body segment, visceral fat, hydration, and the number everybody asks me about: metabolic age.

My Hume scale says my metabolic age is 53.

I'm 71 years old.

Wait — Didn't Your Blood Test Say 56?

Sharp eye. If you read my CardioSmile review, you saw that my Function Health blood work puts my biological age at 56. Now the scale says 53. So which is it?

Honest answer: both, and neither. They're measuring completely different things.

Function Health draws my blood twice a year and runs it through more than 100 biomarkers — lipids, hormones, inflammation, kidney and liver function. Their biological age number comes from what's happening inside my body chemistry.

The Hume scale never touches my blood. It sends a tiny electrical signal through my body and calculates metabolic age from body composition — how much of me is muscle, how much is fat, and where it sits. A 71-year-old carrying the lean mass and fat percentage of a 53-year-old gets a 53.

Two different rulers. Two different numbers. One direction: down. That's the only part I actually care about. Every number I track is public on my Blood Test Results page.

What the Hume Scale Tracks

Hume Body Pod app showing a metabolic age of 53 at age 71This morning it read 184.0 pounds. But the weight is the least interesting part. The app breaks my body into segments — arms, legs, trunk — and shows fat and lean mass for each one. My trunk carries 78.4 pounds of lean mass. My right arm is 10.2% fat. I know these numbers the way I used to know batting averages.

Why does that matter at 71? Because muscle is the retirement account of aging. Sarcopenia — age-related muscle loss — is one of the biggest predictors of frailty, falls, and decline. I can't fight what I can't measure. The Hume scale turns “I think I'm getting stronger” into a chart.

How I Use It

Same time in the morning once a week. After the bathroom, before coffee, minimal clothing. Consistency matters more than precision with any bioimpedance scale — hydration swings the readings, so I control everything I can and watch the trend line, not the daily number.

Thirty seconds on the scale, and the app has already synced before I'm done brushing my teeth (with this, naturally).

The Bottom Line

Is a $200-class smart scale as accurate as a DEXA scan? No. Is it 1,000 times more useful than a dumb scale? Yes.

I'm 71 chronologically, 56 by my blood, and 53 by my body composition. Every one of those numbers is heading the right way, and this scale is how I catch it when they're not.

Get yours here: GaryLeland.com/Hume — that's my affiliate link, which means I may earn a small commission at no cost to you. It helps keep this project going. There's an exclusive discount for 200 Year Life Project readers.

Everything I do is public and free at GaryLeland.com.

A note from Gary: I'm not a doctor, and I'm definitely not your doctor. Nothing here is medical advice. Check with your doctor before you copy anything I do.

Stay sovereign, stay healthy.

My Blood Just Got Two Years Younger: Function Health Results at 71

Blood testing for a healthier future

Twice a year I get my Function Health results back — more than 100 biomarkers pulled from my blood and analyzed. It's the single most important thing I do in my 200 Year Life Project, because it's the one place I can't lie to myself. The scale can be fooled. The mirror can be fooled. Blood doesn't care how I feel — it just tells me what's true.

In June 2026 I got my latest Function Health results back. My biological age came in at 56.

In January 2026, that same blood test said 58.

I'm 71 years old, and in six months my body got two years younger.

What Is a “Biological Age” From Blood?

Function Blood Test ResultsYour chronological age is just the calendar — how many birthdays you've had. Your biological age is how old your body actually behaves, and the two can be wildly different. Two 71-year-olds can be a decade apart on the inside depending on inflammation, metabolic health, organ function, and dozens of other markers.

Function Health draws my blood and runs it through more than 100 biomarkers — cholesterol and lipid particles, blood sugar and insulin, inflammation markers, kidney and liver function, thyroid, hormones, vitamins, heavy metals, and more. It then models a biological age from that whole picture. It's not one number pulled from thin air; it's the sum of what's happening in my chemistry.

That's why I trust it more than anything else I track. You can find every one of these numbers, updated as I test, on my Blood Test Results page. Everything is public.

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CardioSmile Toothpaste Review: My 6-Month Results at 71

The power of nitric oxide toothpaste

I get asked about this one product more than almost anything else in my protocol.

CardioSmile's Breath of Life toothpaste. The world's first nitric oxide–enhancing toothpaste.

I have been brushing with it twice a day for six months. Here's my honest review.

Why a Toothpaste Made It Into a Longevity Protocol

Most people think toothpaste is about cavities. I think about it differently.

Your mouth is a nitric oxide factory. The bacteria on your tongue convert nitrates from food into nitric oxide — the molecule that keeps your blood vessels flexible and your blood pressure in check.

Toothpaste Cardio SmileHere's the problem. Nitric oxide production drops as you age. By your 70s, you're making a fraction of what you made at 40.

And most toothpaste makes it worse. Harsh antiseptics and fluoride formulas can wipe out the very bacteria doing that conversion. You brush your teeth and kill your nitric oxide factory at the same time.

CardioSmile went the other direction. Their toothpaste is designed to support nitric oxide production. Fluoride-free. No harsh antimicrobials.

My Thoughts

What I can tell you for certain: I haven't missed a day, and I take it on the road with me. That's the real test of any product in my protocol. The ones that don't earn their spot get cut.

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Your Mouth Is Trying to Tell You How Long You’ll Live

Your mouth, your longevity

Most people think about dental health the same way they think about getting an oil change. Something you do because you're supposed to. A maintenance task. A checkbox.

That thinking could be costing you years of your life.

The research is now clear: your oral health is one of the most powerful — and most overlooked — predictors of how long and how well you live. At 71, running my own longevity experiment and tracking every biomarker I can get my hands on, I've come to treat my mouth the same way I treat my heart, my brain, and my mitochondria. As a system that needs active protection.

Here's what the science says — and what I'm doing about it.

The Mouth-Body Connection Is Real

Dentist AppointmentFor decades, dentistry and medicine operated in separate silos. Your dentist handled your teeth. Your doctor handled everything else. That model is now officially obsolete.

Certain pathogenic oral bacteria — particularly Porphyromonas gingivalis — have been linked to systemic inflammation and a variety of chronic diseases including Alzheimer's disease, cardiovascular disease, respiratory diseases, and even pancreatic cancer. These bacteria don't stay in your mouth. They enter your bloodstream, travel to your organs, and cause damage far from where they originated.

Oral bacteria have literally been found in arterial plaques and brain tissue. Let that sink in. The bacteria living in your gums can end up in your heart and your brain. This is not a theory. This is what researchers are finding when they open arteries.

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Boosting Nitric Oxide with CardioSmile Toothpaste:

A Fluoride-Free Path to Better Oral Health and Longevity in the 200-Year Life Project

Hey everyone, it's me diving into another tool for the longevity toolkit in the 200-Year Life Project. If you've been following my journey, you know I'm all about stacking habits and products that support vibrant health well into the triple digits. Today, I'm excited to talk about CardioSmile Nitric Oxide Boosting Toothpaste – a game-changer I've recently added to my morning routine. This isn't your average toothpaste; it's designed to enhance nitric oxide production right in your mouth, while ditching fluoride and other toxins. I'll break down the health benefits, why skipping fluoride is a smart move (and what's sketchy about it), the powerhouse role of nitric oxide, and how this ties into our quest for a 200-year life. Let's get into it!

What Is CardioSmile Nitric Oxide Boosting Toothpaste?

Cardiosmile

CardioSmile is a innovative, fluoride-free toothpaste formulated to support your body's natural nitric oxide production starting from the oral cavity. It's packed with ingredients that promote Nitric Oxide levels, which in turn boost circulation to your gums and overall oral health. Unlike traditional pastes loaded with chemicals, this one focuses on remineralizing enamel, enhancing gum health, freshening breath, and nurturing your mouth's microbiome – all without harsh additives. Developed by experts in nitric oxide research, it's aimed at improving not just your smile, but your systemic wellness through better blood flow and reduced inflammation in the gums.
I've been using it for a bit, and my gums feel healthier, with less sensitivity – a win for someone like me optimizing every aspect of aging.

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Walking 2 Miles a Day at 71: Movement Is Medicine

Why I Walk 3 Miles a Day (2 Casual Miles + 1 After Dinner)

At 70 years old, charging toward my wild goal of living to 200 with The 200 Year Life Project, movement is medicine. One of my simplest, most consistent habits is walking—a casual 2-mile walk every day (usually mid-morning or whenever fits) and a relaxed 1-mile stroll after dinner. That's about 3 miles total, low-impact and enjoyable. No rushing, just steady steps outdoors. Science shows even modest daily walking like this slashes mortality risk, boosts heart health, stabilizes blood sugar, and adds healthy years—perfect for radical longevity.

Overall Benefits of Walking 2-3 Miles a Day for Longevity

Walking just 2 miles daily (around 4,000-5,000 steps) meets or exceeds guidelines for reducing chronic disease risk.

walking Studies link it to:

Lower All-Cause Mortality: Even 4,400 steps/day cuts premature death risk by 41%; benefits plateau around 7,500 steps.

Heart Health: Reduces CVD risk by 20-40%, lowers blood pressure/cholesterol, improves circulation.

Metabolic Boost: Better insulin sensitivity, lower diabetes risk.

Brain and Mood: Enhances cognition, reduces dementia/depression risk, boosts BDNF.

Bone/Joint Strength: Prevents sarcopenia/osteoarthritis, supports weight management.

Longer Healthspan: Blue Zones and large cohorts show walkers live healthier longer.

My 3 miles? It's compounding these gains without strain—sustainable for decades.

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Morning Sunlight for Better Sleep: My Sunrise Ritual at 71

Why I Watch the Sunrise Every Morning to Optimize My Circadian Rhythm

At 70 years old, charging toward my goal of living to 200 with The 200 Year Life Project, I've learned that the most powerful longevity hacks are often the simplest—and free. One of my absolute favorites is stepping outside to watch the sunrise every single morning. No matter the weather, I make it a non-negotiable ritual: coffee in hand, eyes on the horizon as the sun crests. This isn't just poetic; it's a science-backed way to anchor my circadian rhythm, boost mood, regulate hormones, and set up deeper sleep and sustained energy for the day.

The Science: Sunrise Light Resets Your Internal Clock

sunriseYour circadian rhythm—the 24-hour internal clock governing sleep, hormones, metabolism, and repair—is primarily set by light exposure. Morning sunlight, especially the mix of red/orange wavelengths at dawn and the blue light spike as the sun rises, signals your suprachiasmatic nucleus (SCN) in the brain that it's daytime.

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Grip Strength

Your Handshake to a Longer Life – Why It's a Key Biomarker for Seniors

Grip StrengthenerAt 70 years old, charging full speed toward my goal of living to 200 with The 200 Year Life Project, I've learned that the simplest metrics often reveal the biggest truths about health. Grip strength—the force you can generate with your hand muscles—has become one of my obsessions. It's not just about crushing a handshake; research shows it's a powerful indicator of overall health, frailty, and even lifespan in seniors like me.

That's why I train with a grip strengthener twice a day, doing 100 reps with each hand, and track my progress with a dedicated grip strength measurement device. If you're over 50 and serious about radical longevity, grip strength should be on your radar too.

Grip Strength as a Vital Sign: The Science Says It's Essential

dynamometerGrip strength is often called a “biomarker of health status” because it reflects your overall muscle function, which ties into everything from mobility to metabolic health. Measured with a dynamometer (that's the device I use), it gauges how much force your hand can apply—typically in kilograms or pounds. For seniors, low grip strength is a red flag for accelerated aging, higher chronic disease risk, and shorter lifespan.

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Sauna Benefits for Longevity: What the Finnish Studies Show

My HOTWORX Infrared Sauna Experience and the Growing Science Behind It

At 70 years old, charging toward my goal of living to 200 with The 200 Year Life Project, I'm obsessed with biohacks backed by solid science. The massive Finnish studies on traditional saunas—showing 40-66% lower all-cause mortality, reduced cardiovascular events, dementia, and stroke risk with 4-7 sessions per week—have had me intrigued. But high-heat traditional saunas can be intense, so before committing to installing one at home, I've been testing HOTWORX infrared sauna pods regularly. Their far-infrared technology, combined with a low-humidity environment (around 120-125°F), makes sessions more tolerable while delivering deep-penetrating heat.

Why HOTWORX as My Trial Run?

HOTWORX's patented far-infrared saunas heat the body directly (not just the air), allowing deeper tissue penetration at lower temperatures. This leads to profuse sweating, better toxin release, and a breathable environment—no overwhelming dry heat. Sessions are 45 minutes with virtual guidance for Hot Iso (yoga/pilates-style) or Hot HIIT, plus 24/7 access. It's the perfect low-commitment way to build heat tolerance and track benefits.

The Expanding Science on Heat Therapy Benefits

While the landmark longevity data comes from traditional Finnish saunas, infrared research is catching up and shows comparable (often complementary) effects due to deeper penetration:

Hot Sauna1. Cardiovascular Health and Longevity
Frequent sauna use mimics moderate exercise: elevated heart rate, improved endothelial function, lower blood pressure, and better arterial flexibility. A 20+ year study linked 4-7 sessions/week to 40-66% reduced all-cause mortality. Infrared studies show similar CV benefits, including reduced blood viscosity and support for congestive heart failure patients.

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Your Coffee May Be Killing You!

Simple Changes May Save Your Coffee.

I love coffee and have been drinking three to four cups a day for years. I never knew about the problems with coffee until recently and want to share that information with you.

I never knew that my coffee was slowly poisoning me.

Simple Changes May Save Your Coffee.

Simple Changes May Save Your Coffee.

First problem: Plastic Pods.

If you’re still using those one-time-use pods, stop today. You’re shooting 185–195 °F water through plastic. That leaches microplastics and nano-plastics straight into your brew. We already can’t escape microplastics in 2025, but we sure as hell don’t need to mainline them at breakfast. Pods also sit in warehouses for 6–18 months → perfect mold factory. Double whammy.

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